SAINBIOSE embodies the commitment of researchers from diverse disciplines – doctors, engineers, and biologists – to work together to improve patient care. Our unit focuses on studying chronic diseases and the aging of the vascular and musculoskeletal systems. By employing a comprehensive approach that combines fundamental, technological, and clinical research, SAINBIOSE aims to advance knowledge and treatment in these critical areas of health.
Vascular and Haemostasis DysfunctionDVH
Platelet & inflammation
Inflammatory and thrombotic responses of platelets to biostress
STB
Biomechanics
STB
Fundamental investigations in the domain of mechanical identification of soft tissues and prostheses, with strong interactions with medical device industries and with clinicians
Inhaled particles
BioPi
Our aim is to improve the understanding of the fate of inhaled (nano)particles in terms of biodistribution, biological activity (therapeutic or toxicological) and biopersistence
Pharmacology & Thrombosis
We focuse on hemostasis pharmacology and multiparametric personalized pharmacology.
Autonomic Nervous System
SNA
Our projects aim at optimizing the regulation of the ANS through physical activity to address cardiovascular disorders.
Biology of osteo-articular tissuesLBTO
Physiopathology
Here, we study the progression of chronic inflammatory diseases and decipher the underlying pathological mechanism toprovide molecular bases for novel biomarkers and treatments.
Regeneration
We take a holistic approach to regenerative medicine for the study of the musculoskeletal system as well as for the repair and regeneration of musculoskeletal injuries and degenerations.
Innovative Exploration of Osteoarticular Tissues
We are a transversal group focused on bone and dental imaging. We conduct qualitative and quantitative studies, using X-ray, and fluorescence imaging. Our research computes bone quality and bone cells parameters of large 3D imaging, and guided superesolution enhancement for cochlear implants, bone loss kinetics.
Prevention
Here, we develop new strategies to prevent bone loss and disease progression, by implementing new counter-measures or new treatments.
Numeric Models
We develop numerical models in order to understand, predict, and optimize biomechanical behaviour of soft osteoarticular tissue in the context of medical contention.
