My academic research lies at the interface of physics, biomechanics, and neuroscience, with a central focus on the role of cerebral vascular pulsations in brain ageing. I study how pulsatility contributes to (i) mechanical stress in brain tissue and vessels, (ii) solute transport and clearance mechanisms, and (iii) the interpretation of physiological signals such as intracranial pressure and related pulse waveforms.

I currently lead the ERC Consolidator Grant BrainSomnia, dedicated to understanding how sleep-related vascular dynamics drive brain clearance and influence dementia risk. I also coordinate BrainPulse SVD, funded by France Alzheimer and IMT, investigating intracranial pulsatility in small vessel disease. In parallel, I collaborate with industry (e.g., Sophysa) to support the design of improved shunt valve technologies for hydrocephalus surgery.

My work is supported by a strong international network, including collaborations with teams in Edinburgh (Royal Society funding), Poland (Campus France funding), and the Leducq international network on brain clearance.

I teach across biomechanics, physiology, and applied mathematics. At Master level (Biomedical Engineering and Mines Saint-Étienne health-focused courses), I deliver lectures and practical sessions on brain biomechanics, blood circulation modeling, solute transport, and fluid–structure interaction in biological systems. I also teach linear algebra and vector analysis to post-baccalaureate pharmacy and engineering curricula.

I obtained my PhD in Physics from the University of Bordeaux (CELIA UMR 5107, 2014), where I developed hydrodynamic models for high-energy density physics and inertial confinement fusion. I then worked as a Research Engineer at CEA (2014–2017), focusing on radiative-hydrodynamics and experimental modelling.

Since 2017, my research has progressively shifted toward biomedical applications, with postdoctoral training in biomechanics and brain fluid dynamics. I conducted a first postdoc at INSERM ToNIC (Toulouse, 2017–2018) on the biomechanics of pathological brain ageing, followed by a postdoc at IMFT (CNRS, Toulouse, 2019–2020) on cerebrospinal fluid–vascular coupling and network modelling in the context of ERC-funded research. I then joined the Department of Mathematics at the University of Oslo (2020–2023), supported by RCN funding, where I developed poroelastic and multiscale models of brain fluid flow and dispersion.

Since 2023, I have been an Associate Professor (Maître de conférences) at Mines Saint-Étienne (SAINBIOSE, INSERM U1059), where I lead research at the interface of physics, engineering, and neuroscience, including the ERC Consolidator project BrainSomnia.

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