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Donata Iandolo, PhD, HDR

CRCN INSERM - Tenured researcher
LBTO
donata.iandolo[@]inserm.fr
Academic interests

My research to date has focused on developing strategies to help the human body respond to an insult such as a bone lesion. My work aims at developing in vitro microphysiological systems that can help us understand if/how bioelectricity plays a role in determining cell differentiation and commitment in the context of bone healing and how we can use it to develop regenerative approaches. We also develop biosensing devices to monitor cell fate and for broader applications in human health.

For the near future I will focus on understanding the bioelectric code of stem cell differentiation into bone-forming cells and of bone to the immune cells’ crosstalk. To this end we will be adopting bioelectronics materials and devices to stimulate and monitor cell responses. I would love to explore new electroactive materials, devices and investigate physiologically relevant interactions between different cell types.

Teaching

I deliver a module on Bioelectronics within the Master 1 Engineering and health at the Ecole des Mines. I also contribute to the MSc in Health Management & Data Intelligence developed by emlyon business school and the Ecole des Mines de Saint-Etienne.

Background

I took my PhD degree in Industrial Biotechnologies at the University “Federico II” in 2010 in Naples. I then worked with Dr Dario Pisignano at the CNR Nanotechnology on various projects around the use of nanofibers for applications in optics but also tissue engineering. In 2013, I moved to Sweden to join the Laboratory of organic Electronics with Prof Magnus Berggren and Prof Daniel Simon. Here I started my journey in the field of bioelectronics and I developed a collaboration with prof Teoh Swee-Hin of the Nanyang Technological University.  This collaboration gave me the opportunity to start my research around the use of electroactive polymers and physical stimuli for bone tissue engineering. In 2016, thanks to a Marie Sklodowska-Curie fellowship, I joined Prof Róisín Owens’ team at the Ecole des Mines de Saint-Etienne in Gardanne (France). The team then relocated to the University of Cambridge in 2017. In 2019 I then moved to Sainbiose. In 2022 I got a position as Lecturer at the Department of Biomedical Engineering at the University of Glasgow and I joined the Center for the cellular microenvironment lead by Prof Manuel Sanchez-Salmeron and Prof Matt Dalby. In February 2023, I reintegrated the Department of Biomaterials at the Ecole des Mines de Saint-Etienne, as Inserm researcher (CRCN).

Publication