Platelet Physiology and Analysis of Their Inflammatory Response to Biostress

Unravelling blood platelets’ contribution to pathophysiological mechanisms related to exogenous (infectious) or endogenous (transfusion) biostress with a focus on circulation, pulmonary and cardiovascular systems.

Combination of ex vivo, in vitro, and in vivo approaches to decipher platelet thrombo-inflammatory responses involved in these mechanisms.

– Thrombo-inflammatory role of platelets in a transfusion context: Improvement and evaluation of platelet concentrate preparation processes to optimize transfusion efficiency and develop personalized transfusion.

– Inflammatory role of platelets in an infectious context: figure out the fundamental mechanisms governing platelet thrombo-inflammatory responses during infection to define new molecular targets to regulate platelet’s anti-infectious inflammatory response.

Since 2010 : Master of Health Engineering (i-Santé): 6hrs ETD/yr, member of master’s juries

participation in PhD monitoring committees

Senior Scientist ((PhD, HDR)

BSL-3 accredidation

Member of the technical experts group of the French Ministry of Higher Education and Research for the “Life, Earth and Environmental Sciences” sector

– Supervising activity: Post-Doc (n=1), PhD (n=4), Master/Bachelor students

– Section associate editor: Frontier in Immunology, Frontiers in Microbiology

Scientific expertise work: Peer-reviewing for international journals (Journal of Translational Medicine, British Medical Journal, Blood, BMC medicine, Thrombosis and Haemostasis, Platelets …); grant application reviewing for theFrench research Agency (ANR).

• Orcid