
My academic interests focus on toxicology and respiratory exposure assessment, with a strong emphasis on advanced in vitro models and organ-on-a-chip systems. My research aims to understand cellular responses to aerosol exposures and to develop predictive toxicology tools for safer respiratory products.
My work adopts mechanistic approaches, including Adverse Outcome Pathways (AOPs), to link early cellular events to adverse outcomes. I mainly investigate inhalation exposure to complex aerosols, including nanoparticles and e-cigarette emissions, using lung-on-a-chip platforms combined with conventional in vitro assays. I am particularly interested in New Approach Methodologies (NAMs) and safe-by-design strategies for risk-relevant toxicity assessment.
My teaching activities primarily take place at Mines Saint-Étienne for engineering students and BMED Master’s students, focusing on biomaterials biological testing and advanced in vitro models. My courses address cell–material interactions and cytotoxicity assessment, as well as experimental approaches for evaluating biocompatibility.
I am also involved in teaching biotechnological approaches to in vitro modeling, including 2D and 3D cell culture systems and organ-on-a-chip technologies within the framework of New Approach Methodologies (NAMs).
I hold a PhD in Process Engineering obtained in 2020 at École des Mines de Saint-Étienne, with a research focus on in vitro toxicity assessment of nanoparticles in pulmonary cells.
My postdoctoral experience includes research at BioPI – Centre Ingénierie et Santé on pulmonary toxicity induced by e-cigarette aerosols, as well as work at CEA within the Horizon 2020 ASINA project, where I developed AOP-based approaches to evaluate nanoparticle toxicity using safe-by-design strategies. I also served as a Contract Teaching and Research Faculty member (invited assistant professor level) in the Department of Pharmaceutical Toxicology at the Faculty of Pharmacy, Lokman Hekim University.
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